Immunohistochemical
ImmunohistochemicalWestern blot
0.5ug/mlPositive Control: Jurkat cell lysate| Product Name | Rabbit anti-PARL polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PRO2207, PSARL, PSARL1, PSENIP2, RHBDS1 |
| Immunogen | The immunogen for anti-PARL antibody: synthetic peptide directed towards the N terminal of human PARL |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMouseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PARL |
|---|---|
| Gene Synonyms | PRO2207 PSARL PSARL1 PSENIP2 RHBDS1 |
| Gene Full Name | Presenilin associated, rhomboid-like |
| Gene Summary | PARL is a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in its gene has been associated with increased risk for type 2 diabetes.This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Alternative Names | PRO2207 PSARL PSARL1 PSENIP2 RHBDS1 |
| Molecular Weight(MW) | 36kDa |
| Sequence | 329 amino acids |
| Entrez Gene | 55486 |
|---|---|
| SwissProt ID | Q9H300-2 |
| Protein Accession | NP_001032728 |
Immunohistochemical
Immunohistochemical
Western blot
0.5ug/mlPositive Control: Jurkat cell lysate| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
