Figure 1: Western blot analysis using anti-PARL monoclonal antibody against truncated Trx-PARL recombinant protein(1) and truncated MBP-PARL(aa112-167) recombinant protein(2).
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain
Tissue Specificity
Purified recombinant fragment of PARL(aa112-167) expressed in E. Coli.
Cellular Localization
Mitochondrion inner membrane; Multi-pass membrane protein
Figure 1: Western blot analysis using anti-PARL monoclonal antibody against truncated Trx-PARL recombinant protein(1) and truncated MBP-PARL(aa112-167) recombinant protein(2).
Application Notes
WB:1:500 - 2000.
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified recombinant fragment of PARL(aa112-167) expressed in E. Coli.