D12S53E ME20 PMEL17 SI SIL gp100 P1 P100 SILV ME20M ME20-M
Gene Full Name
Premelanosome protein
Gene Summary
SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alternative Names
D12S53E ME20 PMEL17 SI SIL gp100 P1 P100 SILV ME20M ME20-M