Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate| Product Name | Rabbit anti-TMEM173 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ38577, ERIS, MITA, MPYS, NET23, STING |
| Immunogen | The immunogen for anti-TMEM173 antibody: synthetic peptide directed towards the middle region of human TMEM173 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | TMEM173 |
|---|---|
| Gene Synonyms | FLJ38577 ERIS MITA MPYS NET23 STING |
| Gene Full Name | Transmembrane protein 173 |
| Gene Summary | TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. |
| Alternative Names | FLJ38577 ERIS MITA MPYS NET23 STING |
| Molecular Weight(MW) | 42kDa |
| Sequence | 379 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Hela cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
