Western blot
Titration: 1.0 ug/ml| Product Name | Nudt15 antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Species Reactivity | Dog,Guinea Pig,Mouse,Rat,Zebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Nudt15 |
|---|---|
| Gene Synonyms | 6530403O17 A730068G11Rik MTH2 |
| Gene Full Name | Nudix (nucleoside diphosphate linked moiety X)-type motif 15 |
| Gene Summary | Nudt15 mediates the hydrolysis of some nucleoside diphosphate derivatives. It can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear. Nudt15 may have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA. |
| Alternative Names | 6530403O17 A730068G11Rik MTH2 |
| Molecular Weight(MW) | 19kDa |
| Sequence | 170 amino acids |
Western blot
Titration: 1.0 ug/ml| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
