Immunohistochemistry
Immunohistochemistry with Small intestine tissue| Product Name | Rabbit anti-OAS1 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IFI-4, OIAS, OIASI |
| Immunogen | The immunogen for anti-OAS1 antibody: synthetic peptide directed towards the middle region of human OAS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHumanMousePigRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OAS1 |
|---|---|
| Gene Synonyms | IFI-4 OIAS OIASI |
| Gene Full Name | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| Gene Summary | This protein is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Alternative Names | IFI-4 OIAS OIASI |
| Molecular Weight(MW) | 47kDa |
| Sequence | 414 amino acids |
| Entrez Gene | 4938 |
|---|---|
| SwissProt ID | P00973-3 |
| Protein Accession | NP_001027581 |
Immunohistochemistry
Immunohistochemistry with Small intestine tissue| Application Notes | WB:1:500~1:2000 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
