Immunohistochemistry
Immunohistochemistry with Tonsil tissueWestern blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart| Product Name | Rabbit anti-OAS1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IFI-4, OIAS, OIASI |
| Immunogen | The immunogen for anti-OAS1 antibody: synthetic peptide directed towards the C terminal of human OAS1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | OAS1 |
|---|---|
| Gene Synonyms | IFI-4 OIAS OIASI |
| Gene Full Name | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| Gene Summary | OAS1 is a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. It is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Mutations in this gene have been associated with host susceptibility to viral infection.This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2',5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described. |
| Alternative Names | IFI-4 OIAS OIASI |
| Molecular Weight(MW) | 42kDa |
| Sequence | 364 amino acids |
Immunohistochemistry
Immunohistochemistry with Tonsil tissue
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human heart| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
