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Rabbit anti-DCK polyclonal antibody - middle region

Catalog Number:OM114514
OM114514
Discount Price
OM114514-100ul
1~2 Week
100ul
OM114514-50ul
50ul
OM114514-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-DCK polyclonal antibody - middle region
Antibody Type Primary Antibodies
Antigen Alias MGC117410, MGC138632
Immunogen The immunogen for anti-DCK antibody: synthetic peptide directed towards the middle region of human DCK
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHumanMouseRabbitRatZebra Fish
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol DCK
Gene Synonyms MGC117410
MGC138632
Gene Full Name Deoxycytidine kinase
Gene Summary Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alternative Names MGC117410
MGC138632
Molecular Weight(MW) 30kDa
Sequence 260 amino acids
Database Links
Entrez Gene 1633
SwissProt ID P27707
Protein Accession NP_000779
Application

Western blot

Host: Rabbit Target Name: DCK Sample Tissue: 293T Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart

Western blot

Host: Rabbit Target Name: DCK Sample Tissue: Jurkat Antibody Dilution: 1.0ug/ml

Western blot

Host: Rabbit Target Name: DCK Sample Tissue: Human Fetal Brain Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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