De oxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
Immunogen
Deoxycytidine Kinase antibody was raised against a synthetic peptide corresponding to N-Terminal residues of Deoxycytidine Kinase (Human).
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
Deoxycytidine Kinase antibody can be used in Western Blot starting at 0.5 - 2 μg/mL, and immunohistochemistry starting at 10 μg/mL.: