Western blot
Host: Rabbit Target Name: GRN Sample Tissue: Thyroid Tumor lysates Antibody Dilution: 1.0ug/ml| Product Name | Rabbit anti-GRN Antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CLN11, GEP, GP88, PCDGF, PEPI, PGRN |
| Immunogen | The immunogen for Anti-GRN antibody is: synthetic peptide directed towards the middle region of Human GRN |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogHorseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | GRN |
|---|---|
| Gene Synonyms | CLN11 GEP GP88 PCDGF PEPI PGRN |
| Gene Full Name | granulin |
| Gene Summary | Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. |
| Alternative Names | CLN11 GEP GP88 PCDGF PEPI PGRN |
| Molecular Weight(MW) | 48kDa |
| Sequence | 438 amino acids |
Western blot
Host: Rabbit Target Name: GRN Sample Tissue: Thyroid Tumor lysates Antibody Dilution: 1.0ug/ml| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
