Western blot
0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate| Product Name | Rabbit anti-SPG20 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | KIAA0610, SPARTIN, TAHCCP1 |
| Immunogen | The immunogen for anti-SPG20 antibody: synthetic peptide directed towards the middle region of human SPG20 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SPG20 |
|---|---|
| Gene Synonyms | KIAA0610 SPARTIN TAHCCP1 |
| Gene Full Name | Spastic paraplegia 20 (Troyer syndrome) |
| Gene Summary | This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). |
| Alternative Names | KIAA0610 SPARTIN TAHCCP1 |
| Molecular Weight(MW) | 73kDa |
| Sequence | 666 amino acids |
Western blot
0.2-1 ug/mlPositive Control: OVCAR-3 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
