Western blot
0.2-1 ug/mlPositive Control: THP-1 cell lysate| Product Name | Rabbit anti-ERCC6L polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | FLJ20105, MGC131695, PICH |
| Immunogen | The immunogen for anti-ERCC6L antibody: synthetic peptide directed towards the N terminal of human ERCC6L |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HorseRabbitRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ERCC6L |
|---|---|
| Gene Synonyms | FLJ20105 MGC131695 PICH |
| Gene Full Name | Excision repair cross-complementing rodent repair deficiency, complementation group 6-like |
| Gene Summary | ERCC6L is a DNA helicase that acts as an essential component of the spindle assembly checkpoint.ERCC6L contributes to the mitotic checkpoint by recruiting MAD2 to kinetochores and monitoring tension on centromeric chromatin. ERCC6L acts as a tension sensor that associates with catenated DNA which is stretched under tension until it is resolved during anaphase. |
| Alternative Names | FLJ20105 MGC131695 PICH |
| Molecular Weight(MW) | 141kDa |
| Sequence | 1250 amino acids |
Western blot
0.2-1 ug/mlPositive Control: THP-1 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
