IHC
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Rabbit anti-ERCC6L Polyclonal antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)IHC
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using Rabbit anti-ERCC6L Polyclonal antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)| Product Name | Rabbit anti-ERCC6L Polyclonal antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Immunogen | Fusion protein of Human ERCC6L. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:50-1:200 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ERCC6L |
|---|---|
| Gene Synonyms | PICH RAD26L |
| Gene Full Name | ERCC excision repair 6 like DNA helicase |
| Gene Summary | This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017] |
| Alternative Names | ATP dependent helicase ERCC6 like antibody ATP-dependent helicase ERCC6-like antibody DNA excision repair protein ERCC 6 like antibody DNA excision repair protein ERCC-6-like antibody ERC6L_HUMAN antibody ERCC 6L antibody Ercc6l antibody Excision repair cross complementing rodent repair deficiency complementation group 6 like antibody Excision repair protein ERCC6 like antibody FLJ20105 antibody MGC131695 antibody PICH antibody Plk1 interacting checkpoint helicase antibody PLK1-interacting checkpoint helicase antibody SNF2/RAD54 family protein antibody Tumor antigen BJ HCC 15 antibody Tumor antigen BJ-HCC-15 antibody |
| Cellular Localization | Centromere,Chromosome,Kinetochore. |
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using Rabbit anti-ERCC6L Polyclonal antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
IHC
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using Rabbit anti-ERCC6L Polyclonal antibody at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)| Application Notes | IHC:1:50-1:200 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
