Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate| Product Name | Rabbit anti-LRDD polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DKFZp434D229, MGC16925, PIDD, LRDD |
| Immunogen | The immunogen for anti-LRDD antibody: synthetic peptide directed towards the middle region of human LRDD |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | LRDD |
|---|---|
| Gene Synonyms | DKFZp434D229 MGC16925 PIDD LRDD |
| Gene Full Name | P53-induced death domain protein |
| Gene Summary | The protein encoded by this gene contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Alternative Names | DKFZp434D229 MGC16925 PIDD LRDD |
| Molecular Weight(MW) | 83kDa |
| Sequence | 753 amino acids |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: NCI-H226 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
