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Rabbit anti-MTRR polyclonal antibody - N-terminal region

Catalog Number:OM117258
OM117258
Discount Price
OM117258-100ul
1~2 Week
100ul
OM117258-50ul
50ul
OM117258-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-MTRR polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias MGC129643, MSR, cblE
Immunogen The immunogen for anti-MTRR antibody: synthetic peptide directed towards the N terminal of human MTRR
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol MTRR
Gene Synonyms MGC129643
MSR
cblE
Gene Full Name 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Gene Summary Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism. Its synthesis is catalyzed by the enzyme methionine synthase. Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor. The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation. It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases. Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alternative Names MGC129643
MSR
cblE
Molecular Weight(MW) 80kDa
Sequence 725 amino acids
Database Links
Entrez Gene 4552
SwissProt ID Q9UBK8
Protein Accession NP_076915
Application

Western blot

Host: Rabbit Target Name: MTRR Sample Tissue: Hela Antibody Dilution: 1.0ug/ml

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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