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Rabbit anti-APRT polyclonal antibody - N-terminal region

Catalog Number:OM117622
OM117622
Discount Price
OM117622-100ul
1~2 Week
100ul
OM117622-50ul
50ul
OM117622-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-APRT polyclonal antibody - N-terminal region
Antibody Type Primary Antibodies
Antigen Alias AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
Immunogen The immunogen for anti-APRT antibody: synthetic peptide directed towards the N terminal of human APRT
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity DogHumanRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol APRT
Gene Synonyms AMP
DKFZp686D13177
MGC125856
MGC125857
MGC129961
Gene Full Name Adenine phosphoribosyltransferase
Gene Summary Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Names AMP
DKFZp686D13177
MGC125856
MGC125857
MGC129961
Molecular Weight(MW) 20kDa
Sequence 180 amino acids
Database Links
Entrez Gene 353
SwissProt ID P07741
Protein Accession NP_000476
Application

Western blot

0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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