Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A549 cell lysate| Product Name | Rabbit anti-CASP5 polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ICE(rel)III, ICEREL-III, ICH-3, MGC141966 |
| Immunogen | The immunogen for anti-CASP5 antibody: synthetic peptide directed towards the middle region of human CASP5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | CASP5 |
|---|---|
| Gene Synonyms | ICE(rel)III ICEREL-III ICH-3 MGC141966 |
| Gene Full Name | Caspase 5, apoptosis-related cysteine peptidase |
| Gene Summary | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc/Max/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. |
| Alternative Names | ICE(rel)III ICEREL-III ICH-3 MGC141966 |
| Molecular Weight(MW) | 43kDa |
| Sequence | 376 amino acids |
| Entrez Gene | 838 |
|---|---|
| SwissProt ID | P51878 |
| Protein Accession | NP_001129581 |
Western blot
0.2-1 ug/mlELISA Titer: 1:312500Positive Control: A549 cell lysate| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
