Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Lung| Product Name | Rabbit anti-RASSF1 polyclonal antibody - C-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | 123F2, NORE2A, RASSF1A, RDA32, REH3P21 |
| Immunogen | The immunogen for anti-RASSF1 antibody: synthetic peptide directed towards the C terminal of human RASSF1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineDogGuinea PigHorseHumanMousePigRabbitRatSheepZebra Fish |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | RASSF1 |
|---|---|
| Gene Synonyms | 123F2 NORE2A RASSF1A RDA32 REH3P21 |
| Gene Full Name | Ras association (RalGDS/AF-6) domain family member 1 |
| Gene Summary | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Alternative Names | 123F2 NORE2A RASSF1A RDA32 REH3P21 |
| Molecular Weight(MW) | 30kDa |
| Sequence | 270 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: Fetal Lung| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
