Western blot
Titration: 1.0 ug/mlPositive Control: THP-1 Whole Cell| Product Name | Rabbit anti-SCARB2 polyclonal antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AMRF, CD36L2, HLGP85, LIMPII, SR-BII, EPM4, LGP85, LIMP-2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | BovineHumanPig |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | SCARB2 |
|---|---|
| Gene Synonyms | AMRF CD36L2 HLGP85 LIMPII SR-BII EPM4 LGP85 LIMP-2 |
| Gene Full Name | Scavenger receptor class B, member 2 |
| Gene Summary | The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). |
| Alternative Names | AMRF CD36L2 HLGP85 LIMPII SR-BII EPM4 LGP85 LIMP-2 |
| Molecular Weight(MW) | 53kDa |
| Sequence | 478 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: THP-1 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
