4933415F16 AA177906 CD150 CDw150 ESTM51 IPO-3 Slam
Gene Full Name
signaling lymphocytic activation molecule family member 1
Gene Summary
Slamf1 is a high-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Alternative Names
4933415F16 AA177906 CD150 CDw150 ESTM51 IPO-3 Slam