Mouse Monoclonal antibody [IPO-3] to CD150High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
IPO-3
Host Species
Mouse
Tested Applications
ELISAFACSIHC-FIP
FACS:1:200~1:500 IHC-F:1:50~1:100 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
CD150 CDw150 SLAM
Target
CD150
Tissue Specificity
CD150 (SLAM)
Cellular Localization
Present on the surface of B-cells and T-cells.
Application Notes
FACS:1:200~1:500 IHC-F:1:50~1:100 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Upon receipt, store at –20°C. Avoid multiple freeze/thaw cycles.