Western blot
Titration: 1.0 ug/mlPositive Control: MDA-MB-435S Whole Cell| Product Name | Rabbit anti-IL6ST polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CD130, CDw130, GP130, GP130-RAPS, IL6R-beta |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HorseHumanPigRabbit |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IL6ST |
|---|---|
| Gene Synonyms | CD130 CDw130 GP130 GP130-RAPS IL6R-beta |
| Gene Full Name | Interleukin 6 signal transducer (gp130, oncostatin M receptor) |
| Gene Summary | The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. |
| Alternative Names | CD130 CDw130 GP130 GP130-RAPS IL6R-beta |
| Molecular Weight(MW) | 35kDa |
| Sequence | 329 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: MDA-MB-435S Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
