Western blot
Titration: 1.0 ug/mlPositive Control: HT1080 Whole Cell| Product Name | Rabbit anti-MASP1 Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CRARF, CRARF1, DKFZp686I01199, FLJ26383, MASP, MGC126283, MGC126284, PRSS5, RaRF |
| Immunogen | The immunogen for Anti-MASP1 antibody is: synthetic peptide directed towards the N-terminal region of Human MASP1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MASP1 |
|---|---|
| Gene Synonyms | CRARF CRARF1 DKFZp686I01199 FLJ26383 MASP MGC126283 MGC126284 PRSS5 RaRF |
| Gene Summary | This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. |
| Alternative Names | CRARF CRARF1 DKFZp686I01199 FLJ26383 MASP MGC126283 MGC126284 PRSS5 RaRF |
| Molecular Weight(MW) | 28kDa |
| Sequence | 699 amino acids |
Western blot
Titration: 1.0 ug/mlPositive Control: HT1080 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
