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Rabbit anti-UNC13D Antibody - C-terminal region

Catalog Number:OM119858
OM119858
Discount Price
OM119858-100ul
1~2 Week
100ul
OM119858-50ul
50ul
OM119858-20ul
20ul
1~2 Week
Product Profile
Product Name Rabbit anti-UNC13D Antibody - C-terminal region
Antibody Type Primary Antibodies
Antigen Alias FHL3, HLH3, HPLH3, Munc13-4
Immunogen The immunogen for Anti-UNC13D antibody is: synthetic peptide directed towards the C-terminal region of Human UNC13D
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity BovineDogGuinea PigHorseHumanMousePigRabbitRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Symbol UNC13D
Gene Synonyms FHL3
HLH3
HPLH3
Munc13-4
Gene Full Name unc-13 homolog D (C. elegans)
Gene Summary This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alternative Names FHL3
HLH3
HPLH3
Munc13-4
Molecular Weight(MW) 119kDa
Sequence 1090 amino acids
Database Links
Entrez Gene 201294
SwissProt ID Q70J99
Protein Accession NP_954712
Application

Western blot

Host: Rabbit Target Name: UNC13D Sample Tissue: Fetal Lung lysates Antibody Dilution: 1.0ug/ml
Application Notes WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles
Storage Buffer phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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