| Product Name | Rabbit anti-IYD Antibody - N-terminal region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C6orf71, DEHAL1, TDH4, dJ422F24.1 |
| Immunogen | The immunogen for Anti-IYD antibody is: synthetic peptide directed towards the N-terminal region of Human IYD |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | IYD |
|---|---|
| Gene Synonyms | C6orf71 DEHAL1 TDH4 dJ422F24.1 |
| Gene Summary | This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4. |
| Alternative Names | C6orf71 DEHAL1 TDH4 dJ422F24.1 |
| Molecular Weight(MW) | 27kDa |
| Sequence | 247 amino acids |
| Entrez Gene | 389434 |
|---|---|
| SwissProt ID | Q6PHW0-3 |
| Protein Accession | NP_001158167 |
| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
