Application
Western blot analysis of IYD Antibody (N-term) in Ramos cell line lysates (35ug/lane). IYD (arrow) was detected using the purified Pab.Application
IYD Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IYD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
IYD Antibody (N-term) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | IYD Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | IYD; C6orf71; DEHAL1; Iodotyrosine dehalogenase 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C6orf71 DEHAL1 |
|---|---|
| Alternative Names | IYD C6orf71 DEHAL1 Iodotyrosine dehalogenase 1 |
| Molecular Weight(MW) | 33360 Da |
| Function | Catalyzes the oxidative NADPH-dependent deiodination of monoiodotyrosine (L-MIT) or diiodotyrosine (L-DIT). Acts during the hydrolysis of thyroglobulin to liberate iodide, which can then reenter the hormone-producing pathways. Acts more efficiently on monoiodotyrosine than on diiodotyrosine |
| Tissue Specificity | Expressed at a high level in thyroid gland and at lower level in kidney and trachea |
| Cellular Localization | Cell membrane; Single-pass membrane protein. |
| Entrez Gene | 389434 |
|---|
Application
Western blot analysis of IYD Antibody (N-term) in Ramos cell line lysates (35ug/lane). IYD (arrow) was detected using the purified Pab.
Application
IYD Antibody (N-term) IHC analysis in formalin fixed and paraffin embedded kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the IYD Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
IYD Antibody (N-term) flow cytometric analysis of Ramos cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
