| Gene Symbol |
APBA1
|
| Gene Synonyms |
D9S411E MINT1 X11 X11A X11ALPHA LIN10 |
| Gene Full Name |
Amyloid beta (A4) precursor protein-binding, family A, member 1 |
| Gene Summary |
APBA1 is a member of the X11 protein family. It is a neuronal adaptor protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilises APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. APBA1 is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. |
| Alternative Names |
D9S411E MINT1 X11 X11A X11ALPHA LIN10 |
| Molecular Weight(MW) |
93kDa |
| Sequence |
837 amino acids |