Application
M6PR Antibody (C-term) (Cat. #AP2792b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow).Application
M6PR Antibody (C-term) (Cat. #AP2792b) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.Application
Confocal immunofluorescent analysis of M6PR Antibody (C-term)(AP2792b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Product Name | M6PR Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | M6PR; MPR46; MPRD; Cation-dependent mannose-6-phosphate receptor; 46 kDa mannose 6-phosphate receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFCIF |
| WB:1:50~100 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MPR46 MPRD |
|---|---|
| Alternative Names | M6PR MPR46 MPRD Cation-dependent mannose-6-phosphate receptor 46 kDa mannose 6-phosphate receptor |
| Molecular Weight(MW) | 30993 Da |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex |
| Tissue Specificity | This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-268 amino acids from the C-terminal region of human M6PR. |
| Cellular Localization | Lysosome membrane; Single-pass type I membrane protein |
| Entrez Gene | 4074 |
|---|---|
| Nucleotide Accession | NP_002346.1 |
Application
M6PR Antibody (C-term) (Cat. #AP2792b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow).
Application
M6PR Antibody (C-term) (Cat. #AP2792b) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application
Confocal immunofluorescent analysis of M6PR Antibody (C-term)(AP2792b) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).| Application Notes | WB:1:50~100 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
