Application
Western blot analysis of M6PR Antibody (N-term)(Cat. #AP2792a) in mouse brain tissue lysates (35ug/lane). M6PR (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term) (Cat.#AP2792a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | M6PR Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | M6PR; MPR46; MPRD; Cation-dependent mannose-6-phosphate receptor; 46 kDa mannose 6-phosphate receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MPR46 MPRD |
|---|---|
| Alternative Names | M6PR MPR46 MPRD Cation-dependent mannose-6-phosphate receptor 46 kDa mannose 6-phosphate receptor |
| Molecular Weight(MW) | 30993 Da |
| Function | Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6- phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex |
| Tissue Specificity | This M6PR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42~71 amino acids from the N-term region of human M6PR. |
| Cellular Localization | Lysosome membrane; Single-pass type I membrane protein |
| Entrez Gene | 4074 |
|---|
Application
Western blot analysis of M6PR Antibody (N-term)(Cat. #AP2792a) in mouse brain tissue lysates (35ug/lane). M6PR (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term) (Cat.#AP2792a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
