Application
Figure 1: Western blot analysis using anti-MAP4K4 monoclonal antibody against truncated Trx-MAP4K4 recombinant protein(1), MBP-MAP4K4(aa300-400) recombinant protein(2) and MAP4K4(aa194-436)-hIgGFc transfected CH0-K1 cell lysate(3).| Product Name | MAP4K4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | HGK; NIK |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 3C7B5 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:500 - 2000. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HGK KIAA0687 NIK |
|---|---|
| Alternative Names | HGK NIK |
| Molecular Weight(MW) | 142101 Da |
| Function | Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha Appears to act upstream of the JUN N-terminal pathway Phosphorylates SMAD1 on Thr-322 |
| Tissue Specificity | Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 9448 |
|---|---|
| Nucleotide Accession | NP_663720.1 |
Application
Figure 1: Western blot analysis using anti-MAP4K4 monoclonal antibody against truncated Trx-MAP4K4 recombinant protein(1), MBP-MAP4K4(aa300-400) recombinant protein(2) and MAP4K4(aa194-436)-hIgGFc transfected CH0-K1 cell lysate(3).| Application Notes | WB:1:500 - 2000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of MAP4K4(aa400-500) expressed in E. Coli. |
