Application
MASP1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MASP1 antibody detected the MASP1 protein (arrow).| Product Name | MASP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MASP1; CRARF; CRARF1; PRSS5; Mannan-binding lectin serine protease 1; Complement factor MASP-3; Complement-activating component of Ra-reactive factor; Mannose-binding lectin-associated serine protease 1; Mannose-binding protein-associated serine protease; |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CRARF CRARF1 PRSS5 |
|---|---|
| Alternative Names | MASP1 CRARF CRARF1 PRSS5 Mannan-binding lectin serine protease 1 Complement factor MASP-3 Complement-activating component of Ra-reactive factor Mannose-binding lectin-associated serine protease 1 Mannose-binding protein-associated serine protease |
| Molecular Weight(MW) | 79247 Da |
| Function | Functions in the lectin pathway of complement, which performs a key role in innate immunity by recognizing pathogens through patterns of sugar moieties and neutralizing them. The lectin pathway is triggered upon binding of mannan-binding lectin (MBL) and ficolins to sugar moieties which leads to activation of the associated proteases MASP1 and MASP2. Functions as an endopeptidase and may activate MASP2 or C2 or directly activate C3 the key component of complement reaction. Isoform 2 may have an inhibitory effect on the activation of the lectin pathway of complement or may cleave IGFBP5 |
| Tissue Specificity | Protein of the plasma which is primarily expressed by liver |
| Cellular Localization | Secreted. |
| Entrez Gene | 5648 |
|---|---|
| Nucleotide Accession | NP_001027019.1 |
Application
MASP1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the MASP1 antibody detected the MASP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
