Application
A. Western blot analysis on 293 cell lysate using anti-MEKK4 RabMAb (Cat. #AJ1471a), dilution 1:1,000.Application
B. Immunohistochemical analysis of paraffin-embedded human ovary adenocarcinoma using anti-MEKK4 RabMAb (Cat. #AJ1471a).| Product Name | MEKK4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAP3K4, KIAA0213, MAPKKK4, MEKK4, MTK1, Mitogen-activated protein kinase kinase kinase 4, MAP three kinase 1 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP551Y |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:1000~5000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0213 MAPKKK4 MEKK4 MTK1 |
|---|---|
| Alternative Names | MAP3K4 KIAA0213 MAPKKK4 MEKK4 MTK1 Mitogen-activated protein kinase kinase kinase 4 MAP three kinase 1 |
| Molecular Weight(MW) | 181685 Da |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 |
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues |
| Cellular Localization | Cytoplasm, perinuclear region (By similarity). Note=Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles (By similarity) |
| Entrez Gene | 4216 |
|---|
Application
A. Western blot analysis on 293 cell lysate using anti-MEKK4 RabMAb (Cat. #AJ1471a), dilution 1:1,000.
Application
B. Immunohistochemical analysis of paraffin-embedded human ovary adenocarcinoma using anti-MEKK4 RabMAb (Cat. #AJ1471a).| Application Notes | WB:1:1000~5000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
