Application
MEKK4 Antibody (C1081) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MEKK4 antibody detected the MEKK4 protein (arrow).Application
MEKK4 Antibody (Center C1081) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MEKK4 Antibody (Center C1081) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MEKK4 Antibody (Center C1081) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MAP3K4; KIAA0213; MAPKKK4; MEKK4; MTK1; Mitogen-activated protein kinase kinase kinase 4; MAP three kinase 1; MAPK/ERK kinase kinase 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0213 MAPKKK4 MEKK4 MTK1 |
|---|---|
| Alternative Names | MAP3K4 KIAA0213 MAPKKK4 MEKK4 MTK1 Mitogen-activated protein kinase kinase kinase 4 MAP three kinase 1 MAPK/ERK kinase kinase 4 |
| Molecular Weight(MW) | 181685 Da |
| Function | Component of a protein kinase signal transduction cascade. Activates the CSBP2, P38 and JNK MAPK pathways, but not the ERK pathway. Specifically phosphorylates and activates MAP2K4 and MAP2K6 |
| Tissue Specificity | Expressed at high levels in heart, placenta, skeletal muscle and pancreas, and at lower levels in other tissues |
| Cellular Localization | Cytoplasm, perinuclear region (By similarity). Note=Localized in perinuclear vesicular-like structures, probably Golgi-associated vesicles (By similarity) |
| Entrez Gene | 4216 |
|---|---|
| Nucleotide Accession | NP_006715.2 |
Application
MEKK4 Antibody (C1081) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MEKK4 antibody detected the MEKK4 protein (arrow).
Application
MEKK4 Antibody (Center C1081) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MEKK4 Antibody (Center C1081) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
