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METAP2 Antibody (N-term)

Catalog Number:OM213635
OM213635
Discount Price
OM213635-100ul
1~2 Week
100ul
OM213635-50ul
50ul
OM213635-20ul
20ul
1~2 Week
Product Profile
Product Name METAP2 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias METAP2; MNPEP; P67EIF2; Methionine aminopeptidase 2; Initiation factor 2-associated 67 kDa glycoprotein; Peptidase M 2; p67eIF2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms MNPEP
P67EIF2
Alternative Names METAP2
MNPEP
P67EIF2
Methionine aminopeptidase 2
Initiation factor 2-associated 67 kDa glycoprotein
Peptidase M 2
p67eIF2
Molecular Weight(MW) 52892 Da
Function Removes the N-terminal methionine from nascent proteins. The catalytic activity of human METAP2 toward Met-Val peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo
Tissue Specificity This METAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human METAP2.
Cellular Localization Cytoplasm. Note=About 30% of expressed METAP2 associates with polysomes
Database Links
Entrez Gene 10988
Nucleotide Accession NP_006829.1
Application

Application

METAP2 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the METAP2 antibody detected the METAP2 protein (arrow).

Application

Western blot analysis of METAP2 (arrow) using rabbit polyclonal METAP2 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the METAP2 gene.
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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