Application
MLXIP Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the MLXIP antibody detected the MLXIP protein (arrow).Application
MLXIP antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MLXIP antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MLXIP Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MLXIP; BHLHE36; KIAA0867; MIR; MONDOA; MLX-interacting protein; Class E basic helix-loop-helix protein 36; Transcriptional activator MondoA |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHE36 KIAA0867 MIR MONDOA |
|---|---|
| Alternative Names | MLXIP BHLHE36 KIAA0867 MIR MONDOA MLX-interacting protein Class E basic helix-loop-helix protein 36 Transcriptional activator MondoA |
| Molecular Weight(MW) | 101185 Da |
| Function | Binds DNA as a heterodimer with MLX and activates transcription. Binds to the canonical E box sequence 5'-CACGTG-3' Plays a role in transcriptional activation of glycolytic target genes. Involved in glucose-responsive gene regulation |
| Tissue Specificity | Widely expressed in adult tissues. Most abundant in skeletal muscle |
| Cellular Localization | Cytoplasm. Nucleus. Mitochondrion outer membrane. Note=Predominantly cytoplasmic but shuttles between cytoplasm and nucleus when associated with MLX. Also associates with the outer mitochondrial membrane and may shuttle between the outer mitochondrial membrane and the nucleus |
| Entrez Gene | 22877 |
|---|---|
| Nucleotide Accession | NP_055753.3 |
Application
MLXIP Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the MLXIP antibody detected the MLXIP protein (arrow).
Application
MLXIP antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MLXIP antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
