Application
A. Western blot analysis on mouse brain lysate using anti-MMP-17 RabMAb (Cat. #AJ1496a), dilution 1:1000.Application
B. Immunohistochemical staining of paraffin-embedded human lymphoma using anti-MMP-17 RabMAb (Cat. #AJ1496a).Application
C. Immunofluorescent staining of HeLa cells using anti-MMP-17 RabMAb (Cat. #AJ1496a).| Product Name | MMP-17 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP17, MT4MMP, Matrix metalloproteinase-17, Membrane-type-4 matrix metalloproteinase |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP1270Y |
| Host Species | Rabbit |
| Tested Applications | WBIHCIF |
| WB:1:500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MT4MMP |
|---|---|
| Alternative Names | MMP17 MT4MMP Matrix metalloproteinase-17 Membrane-type-4 matrix metalloproteinase |
| Molecular Weight(MW) | 66653 Da |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin |
| Tissue Specificity | Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types |
| Cellular Localization | Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 4326 |
|---|
Application
A. Western blot analysis on mouse brain lysate using anti-MMP-17 RabMAb (Cat. #AJ1496a), dilution 1:1000.
Application
B. Immunohistochemical staining of paraffin-embedded human lymphoma using anti-MMP-17 RabMAb (Cat. #AJ1496a).
Application
C. Immunofluorescent staining of HeLa cells using anti-MMP-17 RabMAb (Cat. #AJ1496a).| Application Notes | WB:1:500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
