Application
MMP17 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MMP17 antibody detected the MMP17 protein (arrow).Application
MMP17 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the MMP17 antibody detected the MMP17 protein (arrow).Application
MMP17 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP17 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MMP17 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MMP17; MT4MMP; Matrix metalloproteinase-17; Membrane-type matrix metalloproteinase 4; Membrane-type-4 matrix metalloproteinase |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MT4MMP |
|---|---|
| Alternative Names | MMP17 MT4MMP Matrix metalloproteinase-17 Membrane-type matrix metalloproteinase 4 Membrane-type-4 matrix metalloproteinase |
| Molecular Weight(MW) | 66653 Da |
| Function | Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin |
| Tissue Specificity | Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types |
| Cellular Localization | Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix |
| Entrez Gene | 4326 |
|---|---|
| Nucleotide Accession | NP_057239.4 |
Application
MMP17 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MMP17 antibody detected the MMP17 protein (arrow).
Application
MMP17 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the MMP17 antibody detected the MMP17 protein (arrow).
Application
MMP17 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human uterus tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MMP17 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
