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BAD (Phospho T94)

Catalog Number:OM213987
OM213987
Discount Price
OM213987-100ul
1~2 Week
100ul
OM213987-50ul
50ul
OM213987-20ul
20ul
1~2 Week
Product Profile
Product Name BAD (Phospho T94)
Antibody Type Primary Antibodies
Antigen Alias Bad; Bbc6; Bcl2 antagonist of cell death; Bcl-2-binding component 6; Bcl-xL/Bcl-2-associated death promoter
Modification p-T94
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications DB
DB:1:500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms Bbc6
Alternative Names Bad
Bbc6
Bcl2 antagonist of cell death
Bcl-2-binding component 6
Bcl-xL/Bcl-2-associated death promoter
Molecular Weight(MW) 22080 Da
Function Promotes cell death. Successfully competes for the binding to Bcl-X(L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X(L), but not that of Bcl-2 Appears to act as a link between growth factor receptor signaling and the apoptotic pathways
Tissue Specificity This Mouse BAD Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T94 of mouse BAD.
Cellular Localization Mitochondrion outer membrane. Cytoplasm. Note=Upon phosphorylation, locates to the cytoplasm
Database Links
Entrez Gene 12015
Nucleotide Accession NP_031548.1
Application

Application

Dot blot analysis of mouse BAD Antibody (Phospho T94) Phospho-specific Pab on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.6ug per ml.
Application Notes DB:1:500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.
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