Application
MUM1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MUM1 antibody detected the MUM1 protein (arrow).| Product Name | MUM1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MUM1; EXPAND1; PWWP domain-containing protein MUM1; Mutated melanoma-associated antigen 1; Protein expandere |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EXPAND1 |
|---|---|
| Alternative Names | MUM1 EXPAND1 PWWP domain-containing protein MUM1 Mutated melanoma-associated antigen 1 Protein expandere |
| Molecular Weight(MW) | 78636 Da |
| Function | Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage |
| Tissue Specificity | This MUM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-699 amino acids from the C-terminal region of human MUM1. |
| Cellular Localization | Nucleus. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1 |
| Entrez Gene | 84939 |
|---|---|
| Nucleotide Accession | NP_116242.2 |
Application
MUM1 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MUM1 antibody detected the MUM1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
