Application
Figure 1: Western blot analysis using MUM1 mouse mAb against recombinant fragment of human MUM1.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human melanoma (A), non-Hodgkin`s lymphoma (B), using MUM1 mouse mAb with DAB staining.| Product Name | MUM1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MUM-1; EXPAND1; HSPC211; FLJ14868; FLJ22283; MGC131891; MGC163315; MUM1 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 4G10 |
| Host Species | Mouse |
| Tested Applications | WBIHC |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | EXPAND1 |
|---|---|
| Alternative Names | MUM-1 EXPAND1 HSPC211 FLJ14868 FLJ22283 MGC131891 MGC163315 MUM1 |
| Molecular Weight(MW) | 78636 Da |
| Function | Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage |
| Tissue Specificity | Purified recombinant fragment of human MUM1 expressed in E. Coli. |
| Cellular Localization | Nucleus. Note=Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1 |
| Entrez Gene | 84939 |
|---|---|
| Nucleotide Accession | NP_116242.2 |
Application
Figure 1: Western blot analysis using MUM1 mouse mAb against recombinant fragment of human MUM1.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human melanoma (A), non-Hodgkin`s lymphoma (B), using MUM1 mouse mAb with DAB staining.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human MUM1 expressed in E. Coli. |
