Application
Figure 1: Western blot analysis using anti-MYST1 mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate.Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using anti MOF/MYST1 mAb with DAB staining.Application
Figure 3: Confocal immunofluorescence analysis of Eca 109 cells using anti-MOF/MYST1 mAb (green), showing nuclear localization.| Product Name | MYST1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MOF; KAT8; hMOF |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 8C4C4 |
| Host Species | Mouse |
| Tested Applications | WBIHCIF |
| WB:1:500 - 2000. IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MOF MYST1 |
|---|---|
| Alternative Names | MOF KAT8 hMOF |
| Molecular Weight(MW) | 52403 Da |
| Function | Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex |
| Tissue Specificity | Purified recombinant fragment of human MYST1 expressed in E. Coli. |
| Cellular Localization | Nucleus. Chromosome (By similarity). |
| Entrez Gene | 84148 |
|---|---|
| Nucleotide Accession | NP_892003.2 |
Application
Figure 1: Western blot analysis using anti-MYST1 mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate.
Application
Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using anti MOF/MYST1 mAb with DAB staining.
Application
Figure 3: Confocal immunofluorescence analysis of Eca 109 cells using anti-MOF/MYST1 mAb (green), showing nuclear localization.| Application Notes | WB:1:500 - 2000. IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified recombinant fragment of human MYST1 expressed in E. Coli. |
