Application
NHEJ1 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NHEJ1 antibody detected the NHEJ1 protein (arrow).| Product Name | NHEJ1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | XLF |
|---|---|
| Alternative Names | NHEJ1 XLF Non-homologous end-joining factor 1 Protein cernunnos XRCC4-like factor |
| Molecular Weight(MW) | 33337 Da |
| Function | DNA repair protein involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. May serve as a bridge between XRCC4 and the other NHEJ factors located at DNA ends, or may participate in reconfiguration of the end bound NHEJ factors to allow XRCC4 access to the DNA termini. It may act in concert with XRCC6/XRCC5 (Ku) to stimulate XRCC4-mediated joining of blunt ends and several types of mismatched ends that are noncomplementary or partially complementary |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 79840 |
|---|---|
| Nucleotide Accession | NP_079058.1 |
Application
NHEJ1 Antibody (C-term) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NHEJ1 antibody detected the NHEJ1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM215325