Application
NKRF Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NKRF antibody detected the NKRF protein (arrow).Application
NKRF Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | NKRF Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ITBA4, NRF |
|---|---|
| Alternative Names | NKRF ITBA4 NRF NF-kappa-B-repressing factor Protein ITBA4 Transcription factor NRF |
| Molecular Weight(MW) | 77673 Da |
| Function | Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription |
| Tissue Specificity | Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney |
| Cellular Localization | Nucleus, nucleolus. |
| Entrez Gene | 55922 |
|---|---|
| Nucleotide Accession | NP_060014.2 |
Application
NKRF Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NKRF antibody detected the NKRF protein (arrow).
Application
NKRF Antibody (C-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
