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NXF1 Antibody (N-term)

Catalog Number:OM215814
OM215814
Discount Price
OM215814-100ul
1~2 Week
100ul
OM215814-50ul
50ul
OM215814-20ul
20ul
1~2 Week
Product Profile
Product Name NXF1 Antibody (N-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms TAP
Alternative Names NXF1
TAP
Nuclear RNA export factor 1
Tip-associated protein
Tip-associating protein
mRNA export factor TAP
Molecular Weight(MW) 70182 Da
Function Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5
Tissue Specificity Expressed ubiquitously.
Cellular Localization Nucleus, nucleoplasm. Nucleus speckle. Cytoplasm. Note=Localized predominantly in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex. Shuttles between the nucleus and the cytoplasm. Travels to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA
Database Links
Entrez Gene 10482
Nucleotide Accession NP_006353.2
Application

Application

NXF1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NXF1 antibody detected the NXF1 protein (arrow).

Application

NXF1 Antibody (N-term) (AP14539a)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NXF1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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