Application
PCBP2 Antibody (Cat. #AM1999b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PCBP2 antibody detected the PCBP2 protein (arrow).| Product Name | PCBP2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PCBP2; Poly(rC)-binding protein 2; Alpha-CP2; Heterogeneous nuclear ribonucleoprotein E2 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG2b |
| Clone Number | 376CT13.1.2 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~250 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | PCBP2 Poly(rC)-binding protein 2 Alpha-CP2 Heterogeneous nuclear ribonucleoprotein E2 |
|---|---|
| Molecular Weight(MW) | 38580 Da |
| Function | Single-stranded nucleic acid binding protein that binds preferentially to oligo dC. Major cellular poly(rC)-binding protein. Binds also poly(rU). Negatively regulates cellular antiviral responses mediated by MAVS signaling. It acts as an adapter between MAVS and the E3 ubiquitin ligase ITCH, therefore triggering MAVS ubiquitinationa and degradation |
| Tissue Specificity | Detected in all tissues examined. |
| Cellular Localization | Nucleus. Cytoplasm. Note=Loosely bound in the nucleus. May shuttle between the nucleus and the cytoplasm |
| Entrez Gene | 5094 |
|---|---|
| Nucleotide Accession | NP_001122383.1 NP_114366.1 |
Application
PCBP2 Antibody (Cat. #AM1999b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the PCBP2 antibody detected the PCBP2 protein (arrow).| Application Notes | WB:1:100~250 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
