Application
PPARA Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PPARA antibody detected the PPARA protein (arrow).Application
PPARA Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | PPARA Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPARA; NR1C1; PPAR; Peroxisome proliferator-activated receptor alpha; Nuclear receptor subfamily 1 group C member 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NR1C1 PPAR |
|---|---|
| Alternative Names | PPARA NR1C1 PPAR Peroxisome proliferator-activated receptor alpha Nuclear receptor subfamily 1 group C member 1 |
| Molecular Weight(MW) | 52225 Da |
| Function | Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl- 2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety (By similarity). Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2 |
| Tissue Specificity | Skeletal muscle, liver, heart and kidney. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 5465 |
|---|---|
| Nucleotide Accession | NP_005027.2 NP_001001928.1 |
Application
PPARA Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the PPARA antibody detected the PPARA protein (arrow).
Application
PPARA Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
