MECOM; EVI1; MDS1 and EVI1 complex locus protein EVI1; Ecotropic virus integration site 1 protein homolog
Key Feature
Clonality
Monoclonal
Isotype
IgG1
Clone Number
47AT612.84.88
Host Species
Mouse
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
EVI1
Alternative Names
MECOM EVI1 MDS1 and EVI1 complex locus protein EVI1 Ecotropic virus integration site 1 protein homolog
Molecular Weight(MW)
118276 Da
Function
Functions as a transcriptional regulator binding to DNA sequences in the promoter region of target genes and regulating positively or negatively their expression. Oncogene which plays a role in development, cell proliferation and differentiation. May also play a role in apoptosis through regulation of the JNK and TGF-beta signaling. Involved in hematopoiesis
Tissue Specificity
This PRDM3 antibody was raised using purified recombinant GST fusion protein encoding the N-terminal part of human PRDM3.
Western analysis of extracts from 293 cells using PRDM3 antibody.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.