Application
Western blot analysis of PRL3 Antibody in mouse heart tissue lysates (35ug/lane). PRL3 (arrow) was detected using the purified Pab.| Product Name | PRL3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTP4A3; PRL3; Protein tyrosine phosphatase type IVA 3; PRL-R; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PRL3 |
|---|---|
| Alternative Names | PTP4A3 PRL3 Protein tyrosine phosphatase type IVA 3 PRL-R Protein-tyrosine phosphatase 4a3 Protein-tyrosine phosphatase of regenerating liver 3 |
| Molecular Weight(MW) | 19535 Da |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II |
| Tissue Specificity | Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis |
| Cellular Localization | Cell membrane. Early endosome. |
Application
Western blot analysis of PRL3 Antibody in mouse heart tissue lysates (35ug/lane). PRL3 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
