Application
The monoclonal antibody anti-PRL3 (Cat. #AM8414a) is used in Western blot to detect PRL3 in 293 cells transfected with PRL3.| Product Name | PRL3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PTP4A3; PRL3; Protein tyrosine phosphatase type IVA 3; PRL-R; Protein-tyrosine phosphatase 4a3; Protein-tyrosine phosphatase of regenerating liver 3 |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Clone Number | 111AT714 |
| Host Species | Mouse |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | PRL3 |
|---|---|
| Alternative Names | PTP4A3 PRL3 Protein tyrosine phosphatase type IVA 3 PRL-R Protein-tyrosine phosphatase 4a3 Protein-tyrosine phosphatase of regenerating liver 3 |
| Molecular Weight(MW) | 19535 Da |
| Function | Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II |
| Tissue Specificity | Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis |
| Cellular Localization | Cell membrane. Early endosome. |
| Entrez Gene | 11156 |
|---|
Application
The monoclonal antibody anti-PRL3 (Cat. #AM8414a) is used in Western blot to detect PRL3 in 293 cells transfected with PRL3.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified monoclonal antibody in PBS supplemented with 0.09% (W/V) sodium azide. |
