CRADD, RAIDD, Death domain-containing protein CRADD, Caspase and RIP adapter with death domain;RIP-associated protein with a death domain
Key Feature
Clonality
Monoclonal
Clone Number
EPR1639
Host Species
Rabbit
Tested Applications
WB
WB:1:1000~10000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
RAIDD
Alternative Names
CRADD RAIDD Death domain-containing protein CRADD Caspase and RIP adapter with death domain RIP-associated protein with a death domain
Molecular Weight(MW)
22745 Da
Function
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex
Tissue Specificity
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney